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doi: 10.1038/s41419-022-04775-z 188 MaJZhangHChenYLiuXTianJShenW

Dopamine responses are blunted: Substances like alcohol, nicotine, opioids, and stimulants normally send a surge of dopamine through reward pathways

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For patients on Wegovy with risk factors, monitoring should be individualised based on clinical need, with repeat testing after medication changes, during significant gastrointestinal illness, or if symptoms develop, rather than at fixed intervals

But employers are finding other ways to support workers who want to use those drugs